Expresión de búsqueda: SQUALENE MONOOXYGENASE 
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Descriptor Inglés:   Squalene Monooxygenase 
Descriptor Español:   Escualeno-Monooxigenasa 
Descriptor Portugués:   Esqualeno Mono-Oxigenase 
Categoría:   D08.811.682.690.708.749
Definición Inglés:   The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide. 
Nota Histórica Inglés:   2006(1980); use ETHERS, CYCLIC 1970-1979 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   50664 
Identificador Único:   D050603 

Ocurrencia en la BVS:
 

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